Some of you may have heard of this.

But what if we have it backwards?

Now failure to produce enough insulin is incompatible with life.

And underlying these questions,

Cause and effect.

Let's look at some suggestive facts.

And insulin resistance, as its name suggests, is when your cells get increasingly resistant to the effect of insulin trying to do its job.

I became almost maniacally obsessed in trying to understand the real relationship between obesity and insulin resistance.

I, as you can see, I guess I'm not overweight anymore.

Once you're insulin resistant, you're on your way to getting diabetes, which is what happens when your pancreas can't keep up with the resistance and make enough insulin.

So for many of us, about 75 million Americans, the appropriate response to insulin resistance may actually be to store it as fat, not the reverse, getting insulin resistance in response to getting fat.

Now, most researchers believe obesity is the cause of insulin resistance.

When we become insulin resistant, the homeostasis in that balance deviates from this state.

Logically, then, if you want to treat insulin resistance, you get people to lose weight, right?

So what if we're fighting the wrong war, fighting obesity rather than insulin resistance?

Are you meeting any resistance?

The Resistance?

Resistor color code calculator

Now, my hypothesis, because everybody always asks me, is this.

You don't have any leverage.

That was her fight.

Come on, let's go!

Please don't fight, Maximus.

Don't fight.

You didn't resist.

FBI!

Stay down.

don't fight it.

We help build a resistance.

I dream of a day when our patients can shed their excess pounds and cure themselves of insulin resistance, because as medical professionals, we've shed our excess mental baggage and cured ourselves of new idea resistance sufficiently to go back to our original ideals open minds, the courage to throw out yesterday's ideas when they don't appear to be working, and the understanding that scientific truth isn't final, but constantly evolving.

What is effective? What is the right thing to do?

Oh, a woman who can resist his charms.

Don't resist.

Resistance fighters.

It's a symbol of the Resistance.

But that doesn't mean my bias is wrong, and most important, all of this can be tested scientifically.

(Laughter)

Civil Horizontal Compressor

Civil Vertical Compressor

Civil Bivalent Vertical Rest

Civil Horizontal Rest

Civil Vertical Rest

Circuit Vertical Resistor

Circuit Horizontal Resistor

Couldn't resist.