And this outer layer, this is the vasculature, which is incredible, around a human brain.

Some of you may remember that.

The big change in our understanding of drivers of chronic health in the rich developed world is how important chronic stress from social sources is affecting the immune system, the cardiovascular system.

The heart is taking a quick breather to refill.

Most of this is in developing countries, and the majority is in Africa.

It's gonna be going initially through a giant vessel.

And so specifically you might hear about a coronary artery, or a coronary vein, but together you can call them coronary blood vessels.

Blood runs in the veins.

Blood flows through blood vessels.

And anytime I mention the word vein, I just want to make sure you think of blood going towards the heart.

And the capsules in her blood stream.

So these are the two direction the blood is going to be flowing.

It goes around the ventricle and, as I showed you in the beginning, also around the atrium. It goes all the way up and covers both the left and right side.

Pipe fitters design and assemble pipe systems.

We can do this because tumor blood vessels are unlike normal, healthy vessels we see in other places of the body they're abnormal, they're very poorly constructed, and because of that, they're highly vulnerable to treatments that target them.

Lets divide it out with a large line.

A health status of a nation parallels development of that nation.

Shut your mouth!

like red blood cells.

Subdural hematoma.

You know, where did these things come from?

Thrombosis is the process of a thrombus forming.

I'll write it out again because I want to make sure we see clearly the difference between someone with compliant blood vessels and someone with non compliant vessels.

Lateral pain around thirty degrees of flexion is a positive test.

So let's zoom in on one of them....Maybe we can zoom in right over here, that part of the artery.

But there was something left.

Then you start to take a look at adult life.

Oh,clip that bleeder,Mr. Palmer.

Manage genealogical information, perform genealogical research and analysis

And the bottom curve is the weight of a normal mouse.

So, all these guys over here, these are the true capillaries.

(Laughter)

For example, insufficient angiogenesis not enough blood vessels

This is the human heart.

One individual with very compliant blood vessels and that person as a result of the fact that they are compliant is going to be very happy.

The true capillaries are these guys out here.

If we go down the small pathway a little bit farther, we're entering the era of nanomedicine, the ability to make devices super small to the point where we can design red blood cells or microrobots that will monitor our blood system or immune system, or even those that might clear out the clots from our arteries.

End to end, that would form a line that would circle the earth twice.

Because some of that pressure energy got taken away and stored as elastic energy.

So what you're looking at is basically kind of a mechanistic way of thinking about the heart.

And the Arotic valve is going to be what divides the left ventricle from this giant vessel that we talked about earlier.

All the sudden you could have these clotting factors form a clot right over here right at the actual plaque.

Can't seem to find a vein.

Retract the duct a little more laterally.

And this is an X ray showing you the patent, functional blood vessel.