We can download new diagnostics.

Say a new super bug has emerged.

You've got a lot of pressure favoring antibiotic resistance, so you get increased virulence leading to the evolution of increased antibiotic resistance.

The resistant forms of tuberculosis. There are others.

This, uh,

Your proposal. How half hearted.

Antibacterial earphones, so it's safe.

You're building up a tolerance.

There is a company called Sharklet Technologies that's now putting this on the surfaces in hospitals to keep bacteria from landing, which is better than dousing it with anti bacterials or harsh cleansers that many, many organisms are now becoming drug resistant.

It's like the new sperm donor.

So, you could effectively see how effective your cancer drug treatment is.

Is that what you're gonna tell me? Yeah, well, I was.

They got the organism to evolve to mildness, and they got no development of antibiotic resistance.

We've discovered with AlDS we need cocktails to work well so that the viral resistance we need several anti virals.

Today, Nelson Otwoma is healthy.

There's a new microbe, I just discovered it.

Antibacterial earphones, so it's okay.

So, we can go to the same countries and look and see.

Heat resistance.

And the result of it is, we have diseases.

Dean, how bad is it?

I don't know how much perfume that commercial sold, but I guarantee you, it moved a lot of antidepressants and anti anxiety meds.

In 2002, they were facing a different battle.

Ma Yeah.

Oh, just antihistamines mostly.

Dopamine is associated with romantic love.

I don't know if you know this, but bacteria can actually exchange DNA.

But just a reminder we have about 3.3 million kilograms that are used to treat disease in the human population an increasing amount of that disease, of course, coming from eating the contaminated meat products that are being raised under conditions that produce the antibiotic resistance.

And we study these the most because this might be a good alternative to antibiotics.

It's highly contagious. So it's said. Tularemic meningitis.

But if we look at the end of the 1990s, just half a decade later, we see that in Ecuador they started having a resistance problem.

We say no. WilPharma must...

How do we measure the magnitude of that drug which we refer to as efficacy?

Some bacteria figured out how to stay away from penicillin, and it went around sort of creating its little DNA information with other bacteria, and now we have a lot of bacteria that are resistant to penicillin, because bacteria communicate.

MW

We've taken that universal molecule and turned it around a little bit so that we've made antagonists of the interspecies communication system.

And I can cultivate that intuition in you by just asking you

Well, like the oldschool pharmacopoeia, a tolerance develops, you know.

Two parts thermophilic hydrolase.

And these are sometimes unsafe places to send our sickest patients, especially in an era of superbugs and hospital acquired infections.

But there's another really interesting aspect of this, and this is that if you could control the evolution of virulence, evolution of harmfulness, then you should be able to control antibiotic resistance.

And all of this green stuff here, including the spikes which are because you couldn't get to the pharmacy, or you ran out of drugs, or you went on a three day party binge and forgot to take your drugs, or because you've started to get resistance, or whatever all of that is virus that wouldn't be out there, except for treatment.

Sharon, have you been taking your antiradiation meds?

They either pop the bacterial membrane, they make the bacterium so it can't replicate its DNA.

If you could cause an evolutionary decrease in virulence by cleaning up the water supply, you should be able to get an evolutionary decrease in antibiotic resistance.