Fluorescent

Phosphor

Phosphor

Luminous poisoning? Go on, do what I tell you.

Daylight

Harry's really slow to catch on.

Turn it on turn it off.

But the pay off is really enormous.

The reason that Vibrio fischeri is doing that comes from the biology.

You must steel yourself for a shock, Mr. Bigelow. Well go on, Doctor, what is it you're trying to tell me?

And for that reason, we cover the LED with a phosphor cap.

And now, one way goes from orange to yellow, but the other way goes from orange to...neon yellow.

What's the trouble here?

Now bright, now dimmed, was the moonlight pale,

We're trying to preserve nerves we can't see where they are.

Tell them to prepare a stomach wash for luminous poisoning.

This bacterium has the special property that it makes light, so it makes bioluminescence,

And the cool thing about fluorescence is that it's not only bright, it actually can shine through tissue.

And now, boom, the tumor labels itself and it gets fluorescent.

I must replace that fluorescent lamp.

And this is what I think is the magic of fluorescence.

But one of the most popular ones involves green fluorescent protein.

And this little piece was shown just for the spring session.

In 2008, the Nobel Prize in Chemistry was awarded for work done on a molecule called green fluorescent protein that was isolated from the bioluminescent chemistry of a jellyfish, and it's been equated to the invention of the microscope, in terms of the impact that it has had on cell biology and genetic engineering.

Since August 2012, harmful phosphors have been found in the instant noodle package cups from every famous brand sold in China's supermarkets.

That's a third of the U.S. population.

Stands tiptoe on the misty mountain tops. I must be gone and live, or stay and die.

This is cultures, identical cultures, of cervical cancer cells.

The moon, on the breast of the new fallen snow,

This fluorescent lamp is starting to flicker. We'll have to replace it.

Yes, day and night. As a symbol of longevity.

But even before I peel that muscle away, you saw that there was a tumor underneath.

What needs to happen now is further development of our technology along with development of the instrumentation that allows us to see this sort of fluorescence in the operating room.

It's not that long ago that our lighting was just done with these kinds of lamps.

Well we took the manuscript, and we decided to image it in X ray fluorescence imaging.

The light.

Red light, green light.

Mm hmm.

Photons

photons

The horses were climbing up a hilly piece of road when she first caught sight of a

And when we made a solution of this, tagged with the fluorescence and injected in the body of a mouse, their nerves literally glowed.

However, we've discovered that there's actually no straightforward mechanism to develop a molecule for one time use.

The anglerfish can't glow there by itself, so it holds a sack of glowing bacteria instead.

The sun gives light by day, and the moon by night.