It's gonna be going initially through a giant vessel.

Blood runs in the veins.

Blood flows through blood vessels.

And the capsules in her blood stream.

We can do this because tumor blood vessels are unlike normal, healthy vessels we see in other places of the body they're abnormal, they're very poorly constructed, and because of that, they're highly vulnerable to treatments that target them.

Shut your mouth!

like red blood cells.

Subdural hematoma.

You know, where did these things come from?

Thrombosis is the process of a thrombus forming.

I'll write it out again because I want to make sure we see clearly the difference between someone with compliant blood vessels and someone with non compliant vessels.

So let's zoom in on one of them....Maybe we can zoom in right over here, that part of the artery.

But there was something left.

Then you start to take a look at adult life.

Oh,clip that bleeder,Mr. Palmer.

And the bottom curve is the weight of a normal mouse.

So, all these guys over here, these are the true capillaries.

(Laughter)

One individual with very compliant blood vessels and that person as a result of the fact that they are compliant is going to be very happy.

The true capillaries are these guys out here.

And this outer layer, this is the vasculature, which is incredible, around a human brain.

End to end, that would form a line that would circle the earth twice.

Because some of that pressure energy got taken away and stored as elastic energy.

And so specifically you might hear about a coronary artery, or a coronary vein, but together you can call them coronary blood vessels.

Some of you may remember that.

And the Arotic valve is going to be what divides the left ventricle from this giant vessel that we talked about earlier.

All the sudden you could have these clotting factors form a clot right over here right at the actual plaque.

Can't seem to find a vein.

Retract the duct a little more laterally.

And this is an X ray showing you the patent, functional blood vessel.

So, it's gonna divert and send some of the blood through this way.

The walls are covered with villi where nutrient absorption takes place.

So the body has the ability to regulate the amount of blood vessels that are present at any given time.

Which, in fact, is not a vein at all, but the crustaceans intestinal tract.

The heart is taking a quick breather to refill.

A blood vessel burst inside his brain.

So, those cells are going to need blood vessels supplying them as well. So, that's what the coronary blood vessels are.

Sending abundant amounts of adrenaline into your blood stream.

So I went back to the biology of angiogenesis, and started thinking

We have paper forms to track people who come into clinics.

I woke up to discover that I had a brain disorder of my own.

The revolution is called angiogenesis, and it's based on the process that our bodies use to grow blood vessels.

If you had an acute congestive heart failure, they could bleed a pint of blood from you by opening up an arm vein, giving you a crude leaf preparation of digitalis and then giving you oxygen by tent.

Let's give numbers so we can keep all this straight. This person might have a blood pressure of 160 and the person who is happy with compliant vessels might have a blood pressure of 120.

And this is my right lung on this side.