We can use it from one patient to the next.

It's gonna be going initially through a giant vessel.

Blood runs in the veins.

The true capillaries are these guys out here.

I'll write it out again because I want to make sure we see clearly the difference between someone with compliant blood vessels and someone with non compliant vessels.

So, let's say we follow just the left leg, so this artery over here on the top, it's gonna get a little bit smaller, and maybe I would call this a medium sized artery by this point.

Thrombosis is the process of a thrombus forming.

Blood flows through blood vessels.

And the capsules in her blood stream.

Sending abundant amounts of adrenaline into your blood stream.

This guy's juicing vampires to stay alive.

The walls are covered with villi where nutrient absorption takes place.

The heart is taking a quick breather to refill.

But what we now know, is that for a number of diseases, there are defects in the system, where the body can't prune back extra blood vessels, or can't grow enough new ones in the right place at the right time.

We learn about how that spacecraft works, and so the training is pretty extensive on skills base, so we can be able to do all that plumbing, electrical stuff, water stuff, science stuff.

And the processes that cause this are things like arteriosclerosis for the large vessels or arteriolosclerosis for the small vessels.

The vessels are now a little bit less full of blood because a lot of that blood has already left and gone on to the foot and the face and the different parts of the body.

We can do this because tumor blood vessels are unlike normal, healthy vessels we see in other places of the body they're abnormal, they're very poorly constructed, and because of that, they're highly vulnerable to treatments that target them.

Shut your mouth!

like red blood cells.

Subdural hematoma.

One individual with very compliant blood vessels and that person as a result of the fact that they are compliant is going to be very happy.

You know, where did these things come from?

And this outer layer, this is the vasculature, which is incredible, around a human brain.

And the Arotic valve is going to be what divides the left ventricle from this giant vessel that we talked about earlier.

And so specifically you might hear about a coronary artery, or a coronary vein, but together you can call them coronary blood vessels.

All the sudden you could have these clotting factors form a clot right over here right at the actual plaque.

Can't seem to find a vein.

End to end, that would form a line that would circle the earth twice.

You really do have a way with children, Shrek.

So let's zoom in on one of them....Maybe we can zoom in right over here, that part of the artery.

But there was something left.

Then you start to take a look at adult life.

Oh,clip that bleeder,Mr. Palmer.

They are turning into dead tissue. This process of completely or almost completely depriving cells of oxygen so that they die, this is a heart attack.

And the bottom curve is the weight of a normal mouse.

Well,it's blue because it doesn't have very much oxygen.

So, all these guys over here, these are the true capillaries.

And this is an X ray showing you the patent, functional blood vessel.

And we can then tubularize this scaffold.

Here's a classic example

(Laughter)

Arithmetic deals with numbers.

And this is my right lung on this side.

So you've got a couple of arteries that are branching off and these are also part of the systemic circulation systemic circulation.