The walls are covered with villi where nutrient absorption takes place.

A blood vessel burst inside his brain.

You place the muscle cells on the outside.

In this example here, it's an artery.

So this thrombus right here is going to make it harder for the blood to flow through this vessel.

It goes around the ventricle and, as I showed you in the beginning, also around the atrium. It goes all the way up and covers both the left and right side.

The revolution is called angiogenesis, and it's based on the process that our bodies use to grow blood vessels.

The smallest blood vessels are called capillaries.

Blood flows through blood vessels.

It's gonna be going initially through a giant vessel.

And the capsules in her blood stream.

This is a heart stent developed by Zhong You at Oxford University.

Blood runs in the veins.

Internal haemorrhaging.

You know, where did these things come from?

Or we can build endoscopes that can see deep inside the body around occluders, and also for cardioscopes.

We can do this because tumor blood vessels are unlike normal, healthy vessels we see in other places of the body they're abnormal, they're very poorly constructed, and because of that, they're highly vulnerable to treatments that target them.

So you can imagine if you have these things build up, it's narrowing the actual vessel that's supplying blood downstream from that obstruction.

Shut your mouth!

like red blood cells.

(Laughter)

Subdural hematoma.

And this outer layer, this is the vasculature, which is incredible, around a human brain.

Thrombosis is the process of a thrombus forming.

End to end, that would form a line that would circle the earth twice.

I'll write it out again because I want to make sure we see clearly the difference between someone with compliant blood vessels and someone with non compliant vessels.

Hopefully I'm not confusing too much these medical terms confuse ME a lot but I want to make it very clear, thrombosis is formation of a blood clot inside of a blood vessel than can restrict the flow of blood.

So, all these guys over here, these are the true capillaries.

So let's zoom in on one of them....Maybe we can zoom in right over here, that part of the artery.

All the sudden you could have these clotting factors form a clot right over here right at the actual plaque.

But there was something left.

Then you start to take a look at adult life.

Can't seem to find a vein.

Oh,clip that bleeder,Mr. Palmer.

Retract the duct a little more laterally.

Massive internal bleeding,

And this is an X ray showing you the patent, functional blood vessel.

The heart is taking a quick breather to refill.

He's suffocating. I need to trach him.

And the bottom curve is the weight of a normal mouse.

It had already spread to his lymph nodes, so we used an antiangiogenic skin cream for the lip, and the oral cocktail, so we could treat from the inside as well as the outside.

Now, what I want to clarify is the actual terminology the last video was a little bit hand wavy with the terminology, and I want to go deeper here.

He's a hemophiliac.

Because some of that pressure energy got taken away and stored as elastic energy.

And the Arotic valve is going to be what divides the left ventricle from this giant vessel that we talked about earlier.