I was chilled to the bone.

I was chilled to the bone.

Bone ones are gonna hurt.

He is Japanese to the bone.

I didn't bring a human brain, but I did bring a liter of bone marrow.

He is rotten to the core.

It is a fact that when our organs or tissues are injured, our bone marrow releases stem cells into our circulation.

They've got great potential but haven't yet entered clinical trials.

We're sending his marrow across the country to save the life of a child with leukemia.

Mice with multiple myeloma, an incurable malignancy of the bone marrow, respond dramatically to the treatment with this drug.

You said he was a research pathologist.

Homo Habilis was the first animal to construct tools.

So I thought of a minimally invasive approach, and a new device that we call the Marrow Miner.

One into the deep muscle one into the bonemarrow centres.

We also have adult stem cells throughout our body.

And we all have them.

Heart disease, stroke, diabetes, spinal cord injury, muscular dystrophy, retinal eye diseases are any of these conditions relevant, personally, to you?

I finally got it. Meningitis?

I invented a device called the MarrowMiner, a much less invasive way for harvesting bone marrow.

And adult stem cells are found in you and me in our blood, in our bone marrow, in our fat, our skin and other organs.

And we found, to our surprise, that we not only got bone marrow out, but we got 10 times the stem cell activity in the marrow from the Marrow Miner, compared to the normal device.

The death rate in cancer in over 50 years hasn't changed.

She died. From meningitis?

Some time ago, I made an enemy.

We'll be outside. It's meningitis, isn't it?

Six months later, she comes back with acute myeloid leukemia.

literally cut me in half, I have a scar that wraps around my entire body.

It's all coming back, isn't it?

Possibly spinal fluid.

Venus's clouds are pretty extreme themselves, with temperatures at the base reach a roasting 97 degrees celsius and a bone chilling 8 degree C near the top.

I'm going to show a clip of one young lady.

Brevity is the soul of wit.

He's a spinal surgeon, Ben.

It may encourage more people to sign up to be potential live saving bone marrow donors.

That's not guessing. The child has a fever, headache, stiffness.

It's highly contagious. So it's said. Tularemic meningitis.

Taken from our prize guinea pig this morning.

So Noam and I had this insight that if we want our students to understand how computers work, and understand it in the marrow of their bones, then perhaps the best way to go about it is to have them build a complete, working, general purpose, useful computer, hardware and software, from the ground up, from first principles.

And, so, very quickly, Bob can just get one puncture, local anesthesia, and do this harvest as an outpatient.

too lair em ic ? Tularemic.

Anyway, as you'll see in a moment,

(Laughter)

The bullet didn't touch her spine.

they gave me a spinal tap.

Something which requires a spinal tap.