On the far left, you see the purple line.

Maybe we should be asking ourselves, is it possible that insulin resistance causes weight gain and the diseases associated with obesity, at least in most people?

But what if we have it backwards?

An obese man.

So what if we're fighting the wrong war, fighting obesity rather than insulin resistance?

He is overweight.

A fat boy, too !

And underlying these questions,

Cause and effect.

Let's look at some suggestive facts.

What'd I just watch? (men singing dramatic tune in Japanese) (kid screams) Aah!

I think he's 1 100 pounds of baby fat.

Vicki. Victoria was an overweight Queen.

Inner Party members?

I suffer from obesity.

And the patients started drifting in.

This is what happened to the children of the Dutch Hunger Winter.

And the bottom curve is the weight of a normal mouse.

But obviously the bigger problem that we all know about is obesity, and it's dramatic.

Americans have been told to eat less fat, the percent of calories from fat is down,

So my first topic with respect to this, was not death, but obesity.

So those seem like two bifurcated problems, but I kind of started to think about, you know, what is obesity and hunger?

I was fat as a boy.

In addition, because obesity is not a unicentric epidemic, there's not a Patient Zero of the obesity epidemic if we find that guy, there was a spread of obesity out from him it's a multicentric epidemic.

(Laughter)

Interestingly, one of those birth defects has seen a 200 percent increase in the U.S.

He's a fat boy.

You were deep in the enemy's counsel.

But it may be possible

And the next bar over, the red line, says if your friend's friends are obese, your risk of obesity is 25 percent higher.

The numbers are pretty crazy.

You were the backbone.

the central endocrine gland has been removed.

Can we shrink fat by cutting off its blood supply?

I'm on my third generation of kids that they're getting bigger.

Tokyo is now a center of the world economy.

It's very hard to understand a language, when you're thinking in two languages.

Transportation hubs are prepped and set.

Even after the merger, I'll still be at the heart of things. Thank you. Which means I can hire who I want.

Let's just say value for money.

The last two decades have been the champagne era for dirty lucre.

I did this and lost 40 pounds, weirdly while exercising less.

And just to show you this, this is from the CDC.

Are you packing it on?

Found them in the fat boy's stomach... mixed in with the food.