Pulse abnormal.

I have an irregular pulse.

So ischemia is deprivation of blood flow and oxygen downstream from this right over there.

So in 1980, some researchers did a study on a drug called lorcainide, and this was an anti arrhythmic drug, a drug that suppresses abnormal heart rhythms, and the idea was, after people have had a heart attack, they're quite likely to have abnormal heart rhythms, so if we give them a drug that suppresses abnormal heart rhythms, this will increase the chances of them surviving.

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His bp's spiking.

That's what we call coronary artery disease, or heart disease.

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I thought I'd try to do something about it.

Unfortunately, over the course of the next five, 10 years, other companies had the same idea about drugs that would prevent arrhythmias in people who have had heart attacks.

And it generally travels through two major kind of vessels.

This led me to blood.

Parentral on the other hand, is shown over here.

after her children are asleep to rummage in their minds

So it's more disordered.

There's also another one over here called the superior vena cava, and this is bringing back blood from the arms and head.

I ended up with blunt chest trauma.

Your lungs stop breathing, your heart stops pumping.

Dust Tracks On A Road,

We was just, um... getting rid of stuff we don't need anymore.

My name is Papusay.

A pulse.

And then you've got the capillaries, you've got some blood kind of from both places the pulmonary circulation and the blood from the systemic circulation again mixing.

You really should lock your door.

On the other side you have the mitral valve, which separates the left atrium from the left ventricle.

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Same as ever. This taricardia is killing me.

Maybe beneath her withdrawal she's putting something in order.

It beats in his breast, like everyone else's, be they man or beast?

So blood is headed towards the lungs, going first through the trunk, and of course after the trunk, there is left and right I write that up here pulmonary arteries are next.

And so when people talk about arteries getting blocked or getting clogged, they're talking about the coronary arteries.

So Superior Vena Cava and Inferior Vena Cava.

And let me actually show you where the blood vessels come from. These are called coronary vessels I just write the word coronary here.

We used quantitative arteriography, showing the narrowing.

And then it's gonna come out on the other side, in the pulmonary veins.

And so I think we can roll the video that we have.

This is now going to dump into what we call a venule.

His vitals are spiking.

Pulse ox 90.

While the heart is not moving the surgeon can reroute blood vessels, the part of the heart muscles where clogged arteries are restricting the flow.

So the first branches go and serve the heart. So it's kind of the first to get systemic circulation blood.

And then, when the heart is ready to pump it back out, it goes into this artery, and the name of it is the aorta.

There is actually a little spot right there that they drain in to.

Really simple, but beautiful.