My grandfather was in prison during prohibition.

So we know how to do this in many of the ways that are up there.

We think there's a future to this.

Now, when we talk about suicide, there is also a medical contribution here, because 90 percent of suicides are related to a mental illness depression, bipolar disorder, schizophrenia, anorexia, borderline personality.

Conversely, we know that six million lean people in the United States are insulin resistant, and by the way, they appear to be at even greater risk for those metabolic diseases I mentioned a moment ago than their obese counterparts.

18.Rare diseases

It's similar to the pellagra epidemic in Mississippi in the '30s.

How does that play out in terms of application to a disease?

It's made a mistake.

And many of these chemicals are now linked to the skyrocketing incidents of chronic childhood disease that we're seeing across industrialized nations.

I'll show you an example of that real quickly.

Three years later, he's ripping through boot camp. Attending physician calls the improvement in his bloodcell count miraculous.

Some of you may remember that.

No heart disease, nocturnal asthma or sleep apnea.

This was at a time that treatment actually existed in rich countries.

But now let's apply that to systems diseases like cancer.

And from these extracts, we can reconstruct the human genome at different points in time and look for changes that might be related to adaptations, risk factors and inherited diseases.

90 of people who die by suicide have a diagnosable and treatable mental illness at the time of their death.

Let's move now to a more painful subject.

A little bit down the road from where I was studying medicine was the first major longitudinal analysis of the relationship between how we lived, how we ate, what we smoked, and whether or not we got chronic disease.

For every many with Rheumatoid Arthritis, there are 2 to 3 women who are affected with this disorder.

300 to 500 million cases are reported.

I want to tell you about another disorder.

Now when we talk about suicide, there is also a medical contribution here.

She graduated NYU, she has a heart condition.

Secondly, drug companies are not going to develop really sophisticated psychoactive drugs.

These are years that we could get.

This is a place where the oldest living female population is found.

OK. Now let's move from sleep to diseases.

These little chippies, these things are the size of a credit card.

So the way we develop drugs now is by testing promising compounds on

I have Friedreich's ataxia, a neuromuscular disease.

Because we understand very little about most human diseases.

And as you can see virtually 30 of all disabilities from all medical causes can be attributed to mental disorders or neuro psychiatric syndromes.

When I travel around, I ask my colleagues in biomedical research

The death of Little Nell and Cordelia and all that sort of stuff just doesn't happen anymore.

By switching out that antibody, you can look at a different protein, thus, a different disease potentially any disease in the entire world.

Let's flip the table yet again

Elyn, you don't really understand

Okay, we can start with that. I say no.

Bellini's lymphocemia. It's an autoimmune disease.

It's a national tragedy and scandal that the L.A. County Jail is the biggest psychiatric facility in the United States.

So, it's not an option for low income patients.

She suffers from a chronic illness.

Anders Breivik is merely evil.