An obese man.

He is overweight.

A fat boy, too !

What'd I just watch? (men singing dramatic tune in Japanese) (kid screams) Aah!

I think he's 1 100 pounds of baby fat.

On the far left, you see the purple line.

Vicki. Victoria was an overweight Queen.

I suffer from obesity.

And the patients started drifting in.

This is what happened to the children of the Dutch Hunger Winter.

And the bottom curve is the weight of a normal mouse.

But obviously the bigger problem that we all know about is obesity, and it's dramatic.

Americans have been told to eat less fat, the percent of calories from fat is down,

So my first topic with respect to this, was not death, but obesity.

I was fat as a boy.

Maybe we should be asking ourselves, is it possible that insulin resistance causes weight gain and the diseases associated with obesity, at least in most people?

So what if we're fighting the wrong war, fighting obesity rather than insulin resistance?

He's a fat boy.

But what if we have it backwards?

The numbers are pretty crazy.

Can we shrink fat by cutting off its blood supply?

I'm on my third generation of kids that they're getting bigger.

I did this and lost 40 pounds, weirdly while exercising less.

And just to show you this, this is from the CDC.

Are you packing it on?

Found them in the fat boy's stomach... mixed in with the food.

And underlying these questions,

Cause and effect.

Let's look at some suggestive facts.

In addition, because obesity is not a unicentric epidemic, there's not a Patient Zero of the obesity epidemic if we find that guy, there was a spread of obesity out from him it's a multicentric epidemic.

He was well built, if not fat as such.

PCBs, DDT cross the placenta and effectively determine the likelihood of developing breast cancer and obesity and diabetes already when the baby's in the womb.

And if you're above 25, let's say 25 to 30, then you're in the overweight range.

Why not bring a fat boy, too?

So this approach that we're taking for cancer prevention may also have an application for obesity.

So if you put these physiological processes to work,

Big, but five years old.

People are dying from curable diseases in South Central, Los Angeles.

I did the 23andMe thing and was very surprised to discover that I am fat and bald.

Now how about other exponentials?

But I say to him Fat chance!

I'm sorry, old buddy, but it looks like you're stuck... cleaning up the fat man.

And the next bar over, the red line, says if your friend's friends are obese, your risk of obesity is 25 percent higher.

So I took the food supply of every single country and I compared it to what was actually likely to be being consumed in each country.

She wants to lose weight because she is overweight.