Fluorescent

Phosphor

Phosphor

Luminous poisoning? Go on, do what I tell you.

The GlowintheDark Flashlight!

Harry's really slow to catch on.

Turn it on turn it off.

But the pay off is really enormous.

The reason that Vibrio fischeri is doing that comes from the biology.

You must steel yourself for a shock, Mr. Bigelow. Well go on, Doctor, what is it you're trying to tell me?

What's the trouble here?

Thermosalinographs, fluorometer, carbon analyzer...

Now bright, now dimmed, was the moonlight pale,

Probed

We're trying to preserve nerves we can't see where they are.

Tell them to prepare a stomach wash for luminous poisoning.

And for that reason, we cover the LED with a phosphor cap.

Well, the GlowintheDark Flashlight, that was mine.

This bacterium has the special property that it makes light, so it makes bioluminescence,

That he is about to wire his device into

I must replace that fluorescent lamp.

A firefly?

Hotaru?

And this is what I think is the magic of fluorescence.

But one of the most popular ones involves green fluorescent protein.

Hotarubi!

Hotarubi!

Hotarubi...

And this little piece was shown just for the spring session.

And now, boom, the tumor labels itself and it gets fluorescent.

Since August 2012, harmful phosphors have been found in the instant noodle package cups from every famous brand sold in China's supermarkets.

That's a third of the U.S. population.

Why Hotarubi?

And the cool thing about fluorescence is that it's not only bright, it actually can shine through tissue.

(Sachiko) Hotaru.

This is cultures, identical cultures, of cervical cancer cells.

In 2008, the Nobel Prize in Chemistry was awarded for work done on a molecule called green fluorescent protein that was isolated from the bioluminescent chemistry of a jellyfish, and it's been equated to the invention of the microscope, in terms of the impact that it has had on cell biology and genetic engineering.

This fluorescent lamp is starting to flicker. We'll have to replace it.

But even before I peel that muscle away, you saw that there was a tumor underneath.

Hotarubi

Come.

What needs to happen now is further development of our technology along with development of the instrumentation that allows us to see this sort of fluorescence in the operating room.

And now, one way goes from orange to yellow, but the other way goes from orange to...neon yellow.

It's not that long ago that our lighting was just done with these kinds of lamps.

Locate the base so the ball arm is at a forty five degree (45 ) angle to the T slots