I'll show you an example of that real quickly.

These are years that we could get.

Interestingly, one of those birth defects has seen a 200 percent increase in the U.S.

This is actually the cause of type I diabetes, juvenile diabetes or auto immune diabetes, it has several names.

Occlusion query counter bits

But, as a cancer doc, this is what I see.

Fifty years ago, when I was a medical student in Boston, we were in the midst of the cardiovascular disease epidemic.

She suffers from a chronic illness.

Let's flip the table yet again

18.Rare diseases

So dystonia is a disorder affecting children.

He was taken off the Dutch ship in Martinique and died a week later of consumption. Oh...

This was at a time that treatment actually existed in rich countries.

OK. Now let's move from sleep to diseases.

Fifty percent of the population over the age of 40 suffers from diabetes.

Here's a classic example

So, it's not an option for low income patients.

He's dying. Coronary blockage.

No heart disease, nocturnal asthma or sleep apnea.

The most pressing one is that we want to understand how some differences make some people susceptible to one disease type 2 diabetes, for example and other differences make people more susceptible to heart disease, or stroke, or autism and so on.

They've found a way in that we missed.

So a real skyrocketing of chronic childhood disease that includes other things

300 to 500 million cases are reported.

I want to tell you about another disorder.

Now when we talk about suicide, there is also a medical contribution here.

She graduated NYU, she has a heart condition.

There's a second big project, recently funded by the Wellcome Trust in this country, involving very large studies thousands of individuals, with each of eight different diseases, common diseases like type 1 and type 2 diabetes, and coronary heart disease, bipolar disease and so on to try and understand the genetics.

Similarly, we have the tools with which to ask the question

Three years later, he's ripping through boot camp. Attending physician calls the improvement in his bloodcell count miraculous.

I have Friedreich's ataxia, a neuromuscular disease.

Are you the one that barricaded the alley?

This type of therapeutic approach is showing great promise in terms of other diseases as well, besides cancer, diseases that are also similarly affected by aberrant Epigenetic marks,

The treatment for this is amputation.

Remarkably 1.1 million deaths averted every year.

That's what you're looking at here in the top image.

Some of you may remember that.

Elyn, you don't really understand

Okay, we can start with that. I say no.

Bellini's lymphocemia. It's an autoimmune disease.

It's made a mistake.

It was a study to specifically ask, what's going on with women?

This is a place where the oldest living female population is found.

This map was made for military reasons.

There's a lot of mistakes to be made out there, and the immune system makes them.

Because we understand very little about most human diseases.