And you see activity in some regions we've seen today, medial prefrontal cortex, dorsomedial, however, up here, ventromedial prefrontal cortex, anterior cingulate, an area that's involved in lots of types of conflict resolution, like if you're playing Simon Says, and also the right and left temporoparietal junction.

So you have the prefrontal cortex here,

You idiot!

There's a guy up there in the bleachers, front row.

Well, why didn't you say so?

And so this brief video shows you one of these targets that we're working on now.

We prototyped by CAT scanning the brain out of this animal.

Merry 'fricken Christmas!

And we placed electrodes in area 25, and in the top scan you see before the operation, area 25, the sadness area is red hot, and the frontal lobes are shut down in blue, and then, after three months of continuous stimulation, 24 hours a day, or six months of continuous stimulation, we have a complete reversal of this.

You're a smart man, Muller.

The following in your head!

You were the boss, right?

So this is a model of the human brain, and this is prefrontal cortex, right at the front.

Dance for me, motherfucker.

Right, right?

I used to think you had a brain, man.

The front part of my head.

Use your fuckin' hand.

It's you. It's you, you miserable fuck!

This is the work of Dr. Bruce Miller.

It peaks in early adolescence.

You're sick!

When you get out, it's gonna be for good.

So close to achieving its goal.

It's also, by the way, a characteristic of certain kinds of brain damage.

So here this is the car seat.

Do a little thinking next time, before you use it.

You report to the flight deck.

Police! Let us through!

I call them preposterous.

It goes to the nucleus accumbens, all the way up to the prefrontal cortex, orbital frontal cortex, where decisions are made, high level.

What a bastard you've become.

Whatever! Shut up!

Don't be a fool!

Do not stop before we get to the field.

Last stop before the wilderness.

But humans are different.

So one, two, three, four, five, six, seven 0's.

I shoot you through the brain.

Bow your head before me.

Take Sean, who prefers blue tasting food, such as milk, oranges, and spinach.

One of the big surprises is how limited our attention is, and it comes back to how small and fragile the prefrontal cortex is.

Faster than you. Fucking sick.

What are you doing, you stupid moron?

God will punish you all!