Take the digestive system, for example.

I use the euphemism digestive comfort actually it's a digestive discomfort, which the gut is concerned with.

No mouth, no gut, no digestive system.

And sleep disorders.

Psych... mental disorders.

They are disorders of behavior, and they are disorders of the mind.

Wednesday night is eating disorders.

Fair enough, they are disorders of behavior and they are disorders of the mind.

BL These worms have no digestive system. They have no mouth.

And it lists currently 374 mental disorders.

What drives the disability for these disorders

That what we need conceptually to make a progress here is to rethink these disorders as brain disorders.

The mucosa secrete enzymes that supplement the digestive enzymes of the pancreas and liver.

And it's not just the mortality from these disorders.

These are indeed the chronic disorders of young people.

But it's not just the mortality from these disorders.

These are, indeed, the chronic disorders of young people.

Sometimes you hear people talking about your endocrine system and hormones, sometimes your digestive system.

Depression, there's a great approach to that in mood disorders.

Let's flip the tables now and consider Autism Spectrum Disorders.

The un digestive food reaches the Ileo cecal valve and enters the large intestine or colon.

Now, about a hundred thousand patients in the world have received deep brain stimulation, and I'm going to show you some examples of using deep brain stimulation to treat disorders of movement, disorders of mood and disorders of cognition.

When we decide that everybody with one of these brain disorders, brain circuit disorders, has a behavioral disorder we wait until the behavior becomes manifest.

That is precisely what we do today when we decide that everybody with one of these brain disorders, brain circuit disorders, has a behavioral disorder.

And things like, how the brain miss wires in mental disorders.

Or that could be good clinical targets for treating brain disorders.

Those patterns are risk factors for developing one of these disorders.

And two of the most expensive tissues in our human body are nervous tissue and digestive tissue.

And people feel that, for whatever the reason, it's politically better to use the term behavioral disorders , and to talk about these as disorders of behavior.

Well, autism is the most strongly genetic condition of all developmental disorders.

It's a little different than the way we think about brain disorders

It's a little different than the way we think about brain disorders

and has been linked with disorders of the nervous system and bowels.

Despite the fact that each and every one of these disorders originates in the brain, most of these disorders are diagnosed solely on the basis of observable behavior.

And also these are signals that go awry in disorders such as addiction.

We're going to see electrodes being placed for many disorders of the brain.

Or that eating disorders have the highest mortality rate of all mental illnesses?

What drives disability for these disorders like schizophrenia and bipolar disorder and depression?

Well first because for brain disorders, behavior is the last thing to change.

Well first because, for brain disorders, behavior is the last thing to change.

And now, 14 of the disorders are treatable, two of them actually curable.

Just name your parental anxieties drugs, alcohol, smoking, teen pregnancy, eating disorders, depression.

So I'm very passionate about this research and I really want to continue it and expand it to more disorders besides asthma, more respiratory disorders, as well as more pollutants.

It's one of the cells that seems to be atrophied in disorders like schizophrenia.

like diabetes, and lupus, and asthma, and certain neurological disorders, Huntington's and Alzheimer's diseases.