I think we have found the problem. Your ovarian follicles are still immature.

In the immortal germ line of human beings that is, the eggs that sit in the ovaries they actually sit there in a state of suspended animation for up to 50 years in the life of each woman.

In a female, they would be involved in the ovaries.

It was awesome.

From Conception to Birth Oocyte

In fact, it's one of the biggest problems with chemotherapy today.

And that is where the research began.

Embryonic stem cells have occupied center stage, chiefly because of their pluripotency that is their ease in differentiating into a variety of different cell types.

Some people who have XX chromosomes develop what are called ovotestis, which is when you have ovarian tissue with testicular tissue wrapped around it.

She lays her eggs in other nests

Your ovaries look fine.

But it's taken a long time to get there.

Early Embryo

Then one day, there's a big egg in it.

These are the dissected gonads of an animal that has two testes, two ovaries, another large testis, more ovaries, which is not normal ... (Laughter) even for amphibians.

And the cells that have a haploid number of chromosomes are our gametes, which are sperm cells for men, and ova, or egg cells for women.

This is a research which was done in '86, but it's still valid.

The hen was sitting on the eggs in the nest.

My response, A ton of hardwork and a lot of failures.

They push the other eggs out of the nest

The first cancer was done, which was brain cancer.

Fifty communicable diseases like to travel in human shit.

In some cases, another species like the North American Leopard Frog showed that males exposed to atrazine grew eggs in their testes.

My answer, A ton of hard work, a year and a half to be precise, and a ton of failures.

The protein I found was called mesothelin.

In fact, one in 70 women will be diagnosed with ovarian cancer.

We took the eggs of a related species, a living frog, and we inactivated the nucleus of the egg.

And the germ cells I'll just write it here, just so you get a clear for a male, that's the sperm cells, and for female that's the egg cells, or the ova.

That's the good news.

One in 100 will die from it.

It's not just any cell in the body.

living organisms have been relatively simple single cells.

And so indeed, there are times when we can find ingredients that are bad.

One that has just happened in the last few months is the successful approval of a drug for cystic fibrosis.

The infected cells have a definitive spiderweb look.

This would be sperm.

And then they start with the twin questions

We have more trials planned for lung cancer, pancreatic cancer, ovarian cancer and breast cancer.

She goes home.

It is just your regular protein unless you have pancreatic, ovarian, or lung cancer.

It was pretty depressing.

Now, that first cell that had the potential to become me, it was a product of fertilization, of an egg from my mother so an egg from my mother.

So that means as their mate is sitting on the nest incubating the eggs, the other one is out there foraging, and the longer they have to stay gone, the worse condition the mate is in when the mate comes back.

And when it does it's not going to be that big a deal.

The most exciting thing for Bob Lanza is the ability now to take any kind of cell with induced pluripotent stem cells and turn it into germ cells, like sperm and eggs.